How can we classify red blood cells while they lack nucleus? From my point of view i find it difficult to be classified as we have all cells with nucleus, even prokaryotic cells which have no nucleus membrane but they have a nucleus material which is DNA. Maybe if we classify it as a type of cell which lacks nucleus and others are cells with nucleus
RBCs have nuclei until the nucleus is removed in the spleen; presumably this occurs after the cell has filled with hemoglobin and so as to make RBCs efficient and flexible.