prostate cancer punnet square help needed

Question

Obviously only men can get prostate cancer. So if a husband and wife want to start a family and the husband has prostate cancer what is the chance they have a boy with prostate cancer? I don't get how to set up the punnet square. Thanks

Answer 1

There are far too many unanswered questions to confirm before we answer the main question. First, I looked it up, and prostate cancer, at least genetically, seems linked to a mutation in 2 different genes, so you would have to account for them. Next, I don't think either of the aforementioned genes are on the x or y chromosome, which means that a female could be a carrier for the mutation (and as a not-so-fun-fact, mutation of those genes in women are linked to breast cancer). Third, we would have to confirm whether a mutation on those genes are dominant or recessive for prostate cancer. So these, and probably other, concerns have to be answered before we can make a punnet square.