Christopher M. answered 05/27/16
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The answer above is an excellent overview but it misses some important factors. First is certainly the invention of the cotton gin. Before its invention, plantation style agriculture of cotton was nearing the point of being unprofitable, but the invention of the cotton gin created an economic boom for the Southern planter class and firmly cemented the status of "King Cotton" in the South. The ownership of slavery among the political elites is another significant factor, almost every major President before the Civil War minus the two Adams, and some of the Whigs were slave owners. Most our major founders were slave owners, though many had changes of heart about the issue. As a result, our founding documents did not seek to limit slavery, only providing an expiration date for the slave trade's illegality. The above answer is very much so correct on the influence of Greek and Roman ideals. Our founders believed in the Roman concept of Liberty, which meant certain rights for established people but allowed for slavery and lower status individuals. This is different from the German concept of Freedom which is often mistaken for that of Liberty and believes in rights for all people. Thus our founding documents are descended directly from the philosophy of the slave-state. In fact, John Locke, the biggest philosophical influence on our founders, wrote South Carolina's state constitution and in it explicitly condoned slavery. The three-fifths compromise however is misplaced. It was actually the Plantation Owners who fought for slaves to be counted as full-persons for representation purposes, and the anti-slavery northerners who fought against them being counted as persons. The three-fifths compromise only helped boost slavery in the sense that it provided political incentive to some elites to maintain slavery to boost their electoral representation, but in essence likely had little impact relative to the other factors. But it is true that slaves were not considered people with rights under the Constitution. But according to the Dredd Scott decision, which declared it so, it is because the founders wrote of freedom and equality for all men at the same time they owned slaves, which the Court found indicative that African-Americans were never to be considered free-men by the founders. And lastly, you have the unwillingness of Northerners to push for abolition of people in the South they did not know or see for much of our history, especially if pushing for that would lead to open conflict. As a result, congress passed several famous compromises (the Missouri for example) to insure a balance that would result in a continuation of the status quo.