The water molecules will "look" the same. There will be no change in their shape or structure.
The increase in temperature will cause more collisions, however.
As the temperature continues to rise, some of the molecules will escape as vapor.
Once the vapor pressure of the heated water reaches the atmospheric pressure, the water will boil. The temperature at which water will boil will vary with the atmospheric pressure. At one mile above sea level, for example, water will boil at about 180 degrees. At the bottom of a mine, water will boil at temperatures above 212 degrees.