Ryan C.
asked 10/30/13Describe the structure, function, and life history of red blood cells?
2 Answers By Expert Tutors
L Jacque C. answered 12/06/13
Finally find Joy in Biology, Anat/Physiol, Pharmacology, Study Skills
Describe the structure, function, and life history of red blood cells? Sorry I join late I'm new to the blog.
Structure and function of RBC critical to understand: Think and read briefly about Sickle Cell Anemia (sickle shaped) and other RBC disease conditions would include; Hereditary Spherocytosis (ball shaped), or Sideroblastic Anemia (RBC too small).
Shape or anatomy of the RBC determines function! Know this fact and don't forget it; normal RBC's are BI-CONCAVED (go look it up and find pictures and let it burn into your memory!)
Why is the term BICONCAVE important to RBC's? Undulations (like pictures of the lock ness monster) creates increased SURFACE area so as to expose the RBC membrane to larger quantities of O2 absorption and CO2 expulsion (gas exchange). If the BI-CONCAVITY shape is lost, gas exchange is decreased and the organs in the body start to complain (heart-chest pain, lungs-fatigue, brain-can't think).
Contents of RBC's: see Naina B. great summary. Also Hemoglobin equals Heme: Iron in Ferrous form (just like in your vitamins or Iron is a sword) and Globin: is a globular protein (DETAILS not necessary: critical defect in Sickle Cell Anemia-switch between the amino acid Valine and Glutamic Acid by way of a DNA point mutation which changes the normal shape of Hemoglobin also resulting in decreased affinity or attractiveness of O2 and again the body organs complain).
Life History of RBC's: exist for approximately 120 days (4 months). RBC's are "born" or created in the red bone marrow of long bones (scapular, femur, humerus, some in the skull and scapula). RBC's "die" or are re-cycled in the Spleen (breaks the cell membrane down, and the protein globin is separated into its building blocks-peptides and amino acids and finally Heme).
Naina B.
12/06/13
Naina B. answered 10/30/13
Naina, a versatile tutor
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L Jacque C.
12/06/13