John E. answered 09/15/22
High School Mathematics Teacher currently working for NASA
This is a very long problem to write out in "Ask An Expert" my recommendation would be to come up with the integers you can get and then ask the specific ones you can't come up with or reach out to a tutor to schedule a session to go through this problem in-depth.
For instance to get 3 you could do (1+2)5-4 so on and so forth.