
Brian M. answered 06/21/22
Biology Tutor With Over A Year Of Experience Tutoring
The main difference between the two has to do with how the phosphate group is added to ADP. In substrate-level phosphorylation, the phosphate group is added from an attached organic molecule. In oxidative phosphorylation, an inorganic phosphate is added by the proton-motive force generated from the electron transport chain.