Why are proteins in the insoluble form when they are in frozen water?

Question

Why would lowering the temperature of water change the intermolecular forces so much that proteins once soluble in water, become insoluble? I know freezing can create a crystal lattice, but I don't see how temperature would connect to the inter-molecular forces of water? If it even does?EDIT: So why would a temperature decrease change how a protein interacts with a POLAR solvent

Answer 1

As the temperature decreases, you approach freezing (duh). But when you think about what that means, it means that the molecules are moving around less and becoming more ordered. As the solvent molecules (aka water) get closer together, the intermolecular forces get stronger, leaving less water available to solubilize the protein.