Independent assortment

Question

How would you demonstrate that two loci are independently assorting? Locus A has two possible alleles, A1 and A2, and Locus B has two possible alleles, B1 and B2. Should I uses a punnet square?

Answer 1

A Punnett square can help demonstrate independent assortment, but the best way to demonstrate is to first identify the four possible combinations of alleles that can occur in gametes during meiosis.

If these alleles assort independently, there is an equal chance for each of these combinations:

A1B1, A1B2, A2B1, A2B2 (25% chance for each of these combinations)