The ANS regulates HR and BP via the SNS and PNS to maintain homeostasis. The SNS increases HR and BP in response to stress or activity by releasing norepi, which stimulates beta-1 adrenergic receptors on the heart, enhancing chronotropy (HR) and inotropy (contractility). The PNS, via the vagus nerve, decreases HR by releasing ACh, which acts on muscarinic receptors to slow HR. These systems work in opposition, with the SNS promoting activation during stress and the PNS promoting relaxation.
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