The maximum rate of change is in the direction of the gradient of the function which is a vector made up of the partial derivative of f with respect to x and the partial derivative of f with respect to y.
∇f= <2x-12y, -12x+2y>
∇f(1,1) =<-10, -10>
The direction of the minimum rate of change is in the opposite direction of the gradient.
<10,10>