An infection arising in the 5th toe will cause inflammation of what group of lymph nodes first?

Question

This question stems from understanding lymph node drainage. While this specific questions focuses on an infection of the lower anatomy, the lymph drainage can be traced in a specific order until it returns to systemic circulation.

Answer 1

Chiefly the popliteal nodes. There’s a handful of these little nodes in fat pad of the popliteal fossa. Lateral vessels drain into this.

Answer 2

Popliteal lymph node group.