biochemistry qustion

Question

1.The process of protein folding and aggregation of hydrophobic molecules in aqueous environment is described bioenergitically as _______ ?

A. having positive ΔG^o’

B. having negative ΔG^o’

C. endergonic

D. having K_eq value of 0.01

E. having zero ΔG^o’

If the reaction below has ΔGo’ = + 9.7 Kcal/mole :    glucose  +  PO43– → glucose-6-P

 How many minimum ATP hydrolysis is required to make this reaction exergonic ?

1. one
2. three
3. four
4. none
5. two

Answer 1

1. I believe the answer is B because the mixing of hydrophobic molecules and water is not a spontaneous reaction. Hence, bioenergetically it would be described as having a negative delta G knot.
2. One ATP would be required to make the reaction exergonic because Glucose is phosphorylated to give rise to glucose -6-P via the enzyme Hexokinase. Only one ATP would be hydrolyzed.