Bella:
The best way to do this is to draw your two triangles in the proper quadrants. From there you can determine that in Quadrant II, the Cos(B) = -4/5 and in Quadra IV, the Cos(A) = +3/5 by the Pythagorean Thm or by noticing that we have a Pythagorean 3-4-5 triple. We already know that Sin(A) = -4/5 and Sin(B) = 3/5. Hopefully you used the Pythagorean Thm or the concept of a Pythagorean triple to determine the values not given to you. With all these 4 important trig functions, and by knowing the identity that
Cos(A+B) = CosACosB-SinASinB we get (3/5)(-4/5) - (-4/5)(3/5) or -12/25 - (-12/25) or -12/25 + 12/25 = 0