Lol L.
asked • 11/19/21how catechin (from tea) inhibit glucotransferase?
in great detain explains ways or techniques of how catechin contribute in inhibiting glucotransferase enzyme to aid in reducing dental caries.
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1 Expert Answer
Catechins inhibit glucosyltransferase by directly binding to the enzyme’s active site, which prevents proper substrate binding.
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Muhammad W.
Catechins inhibit the glucosyltransferase enzyme by binding to it, blocking substrate access, and preventing glucan synthesis — thereby disrupting bacterial adhesion and biofilm formation. This biochemical interference is a key reason green tea polyphenols are considered natural anticariogenic agents.21d