(x-4+i)(x-4-i)(x-5)(-5)
expand and it's a 3 degree with leading coefficent -5
=(x^2-8x+16+1)(x-5)(5)
= -5x^3 + 65x^2 -285x + 425
just change the sign of each zero, add an x, then multiply them all together, along with -5 to get the leading coefficient = -5