Are you asking about the biologic mechanism, neurochemical mechanism, or kinetic mechanism, or some other type of mechanism? The question is incredibly broad and vague and impossible to answer in its current form. In addition, when it comes to alcohol tolerance, there are different types, e.g. functional tolerance, metabolic tolerance, acute tolerance, and "acquired" tolerance can apply to different types. This also adds to the complexity of the question. Sorry I can't be more helpful, but the question is just too broad in its current form.
Inactive Tutor
It offers a resource instead of why an answer can’t be given. Thanks for your question. Take care of yourself!09/15/19