Asked • 07/19/19

How do lipid-soluble substances diffuse through the cell membrane?

It’s said that water-soluble substances can diffuse through cell membrane with less ease than lipid-soluble substances because the former encounters impedance in the hydrophobic region of the phospholipid bilayer. However, does the same logic not apply for hydrophobic substances, in that they cannot traverse the hydrophilic outer/inner surfaces of the plasma membrane? How would they be able to enter or leave the cell with greater ease?

1 Expert Answer


Dip P. answered • 07/24/19

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Experienced Science Tutor (Bio, biochem, chem, physics)

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