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Asked • 06/13/19

Why does ammonium oxalate cause swelling of RBCs?

From *Pre examination procedures in laboratory diagnosis* by Walter Guder :> ...It consists of three parts by weight of ammonium oxalate which> causes swelling of erythrocytes balanced by two parts of potassium> oxalate which causes shrinkage...This is regarding use of oxalates as anticoagulants. To me, it makes sense that potassium oxalate causes shrinkage of erythrocytes but i don't understand why Ammonium oxalate causes swelling. Is it because it converts to Ammonia in alkaline pH of blood, diffuses into the RBC and converts back to ammonium.

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