Equation has the form y = a(x-h)2 + k, where (h,k) is the vertex..
The x-coordinate of the vertex lies halfway between the x-intercepts. So, h = 2.
y = a(x-2)2 + k
Since the points (4,3) and (-1, 0) are on the graph, we obtain the system of equations:
4a + k = 3
9a + k = 0
Subtract the equations to get -5a = 3. So, a = -3/5.
Then, -27/5 + k = 0
k = 27/5
Equation: y = (-3/5)(x-2)2 + 27/5.