In Algebra I and II, it would be inappropriate to discuss derivatives. Derivatives aren't explored until Calculus.
However, the use of graphing to determine minimums and maximums is a common tool. Also, for parabolas, it is known at this level that the min/max occurs when x = -b/(2a), with ax2 + bx + c = 0.
T(t)=−0.03t2+ 0.72t+ 97.7,
So, t = -0.72/(2*(-.03)) = 12 hours after the illness begins.
T(12) = 102.02, which is 102.0, rounded to one decimal place.
No calculus required! And this can easily be checked on a graphing calculator.