First I'm going to assume that the Revenue equation has a typo because 13x/x = 13, so I think the x in the denominator is supposed to be a number, let's say 2 in this case.
a) Like the prompt says you want to take P(x) = R(x) - C(x) = (13x/2+4) - (x+3) and simplify this, remember to distribute the negative. You can't sell less than 0 calculators, so x > 0 is your restriction. Also, x needs to be an integer (whole numbers) since you can't sell half a calculator.
b) To find the break even point, you need to set R(x)=C(x) and solve for x. Remember that x = calculators, so this will tell you how many calculators need to be sold to "break even". You can think about this in the real world. If you make (revenue) as much as you paid (cost), then you will break even. Notice that is the same as having 0 profit, or P(x) = 0 (and solve for x).
c) You can tell that you won't make a profit if your P(x) is negative for any x > 0 or like they are suggesting, the x-intercept of your profit function is a negative x value, but you can't sell a negative amount of calculators. To fix this, you would need more revenue, meaning that the number attached to the x value in the R(x) needs to be larger, which implies that you are charging more per calculator.
d) For the bold text, we know that x = calculators sold, so it makes no sense if x was negative, and is really concerning if your x-intercept of P(x) (which represents your break-even point) is negative.