Your null hypothesis Ho: p0 (the proportion than develop nausea) = 0.20
Your alternate hypothesis Ha: p0 > 0.2
You will use a one proportion z-test to verify the claim in the alternative hypothesis.
You first need to compute the sample proportion phat = number who develop nausea/total number of subjects.
You will then need to compute the z-statistic: (phat - p0)/sqrt(p0* (1-p0)/n), where n is the total number of subjects and p0 is the value under the null hypothesis (0.2).
Use the standard normal probability table to compute the probability that z > the above computed z-statistic. That is your p-value. If the p-value is less than 0.01, you can reject the null hypothesis.