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Asked • 05/24/19

Why does the affinity of haemoglobin's for oxygen decrease at high altitudes?

My class 12 NCERT book says, Pg 226> The body compensates low oxygen availability by increasing red blood cell production, decreasing the binding affinity of haemoglobin and by increasing breathing rate.Why should the haemoglobin binding capacity decrease at high altitude?I think it should increase for better oxygen transfer and uptake from air. The concentrtion of oxygen in the atmosphere decreases with height. Hence, if the haemoglobin binding increases, we will be able to draw more oxygen from the air and transport it to the cells.

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Cecil H. answered • 05/24/19

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Biochemist with 8+ years experience

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