J.R. S. answered 09/18/14
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The procedure to follow in a laboratory setting is to weigh the compound of interest and then heat it to above 100 degrees C (assuming it doesn't melt) to drive off all the water of hydration. Then weigh the compound again, and continue to heat and weigh until the weight remains constant. This suggests all the water has been eliminated. The difference in the initial weight and final weight represents the weight of water. Moles of water = mass of water/18.