Inactive Tutor answered • 02/16/18
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Williamson ether synthesis is an SN2 reaction, thus it is preferable to use the polar aprotic solvent like acetonitrile. Toluene is not very polar.
Connie C.
asked • 02/15/18Williamson Ether Synthesis LAB QUESTION!?
Why use acetonitrile instead of toulene in a Williamson Ether Synthesis? (Phenol, NaH, 1-bromopropane)?
Also, why use aqueous Na2CO3 instead of distilled water when extracting?
Also, why use aqueous Na2CO3 instead of distilled water when extracting?
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