The point is in second quadrant, so the cosine, tangent, secant, and cotangent are negative and the sin and cosecant are positive. The hypotenuse is sqrt (4 + 100) = sqrt(104) = 2 sqrt(26). I take the approach of thinking of opp adj and hyp are being the positive absolute values (opp = 10, adj = 2, hyp = 2 sqrt(26) ) and using the quadrant rule to determine the signs. So
sin = opp/hyp = 10/(2 sqrt(26)) = 5 sqrt(26)/26
csc = 1/sin = srtt(26)/5
cos = - adj/hyp = - 2/(2sqrt(26)) = - sqrt(26) / 26
sec = - 1/cos = - sqrt(26)
tan = - opp/adj = - 10/2 = -5
cot = 1/tan = - 1/5