100 mg of Drug A was administered. analysis of the patient’s blood concentration was: Drug A 10 micrograms/L =10,000 liters. What is the Vd?

Question

drug dose calculations

Answer 1

 

V_d = volume of distribution and is a theoretical volume.

10 micrograms x 1 mg/1000 micrograms = 0.01 mg

So, you can express blood concentration as 0.01 mg/L to keep units the same as that used for the dose.

100 mg x 1 L/0.01 mg = 10,000 L = V_d <== Answer.

Answer 2

Hi Molly,

The question has a flaw. Drug A 10 micrograms/L = 10,000 liters?

Please correct and you could get some answer.

Best

Sanjay