We know that Distance = Rate x Time
We are given R1 = 50mph, R2 = 65mph, and Time = 4 hours
So, at R1, the Distance will be 50mph x 4h = 200miles
At R2, the Distance will be 65mph x 4h = 260miles
Therefore, Distance will be equal to or more than 200 miles (=> 200 miles), but less than or equal to 260 miles (<= 260 miles)
None of the choices you gave fit the answers. Perhaps the choices were copied incorrectly.