Administration of epinephrine with a local anesthetic may result in the reduction of arterial diastolic blood pressure due to stimulation of what receptor?

Answer 1

Administration of epinephrine with local anesthetics may result in a reduction in diastolic arterial pressure due to the stimulation of Beta-2 adrenergic receptors. This mechanism, along with Beta-1 mediated tachycardia, can warn of intravascular injection of local anesthetic.