
Stanton D. answered 01/25/21
Tutor to Pique Your Sciences Interest
Hi Dawson H.,
Xulai above answered almost correctly. But, an overriding rule in performing calculations of this type is, "preserve all data you are given, and round only once to express your final answer.
So: 7.61/(13.4-8.17) = 1.455... rounds to 1.5 . Same answer, in this case .... but not necessarily in general!
Rounding more than once is a tremendous no-no in data preparation in industries which are regulated, such as pharmaceuticals. And that includes data preparation "in parallel", for EACH reported datum.
Give you an example: a dosage form (a tablet) is found to contain 15.555 mg of an active ingredient, when it was labeled as containing 15 mg. Although the report may contain a statement of content in mg and also as %of label claim, each to be rounded to 1 decimal place, the mg would be reported (rounded) as 15.6 mg, but the %label claim would be calculated from the 15.555, as 103.7% (NOT 104.0% as 15.6 mg would imply). I can't tell you how much grief this causes beginning chemists (and this simple example is trivial compared to cases with multiple reported impurities, each with its own analytical criteria (limit of detection and limit of quantitation), but it's required (by government regulations), so that each datum reported is (each) as accurate as possible.
-- Cheers, --Mr. d.