Heyam K.

asked • 10/11/20

Provide the reaction conditions for the acidic cleavage of ethers.Give an exampleof the reaction.

Provide the reaction conditions for the acidic cleavage of ethers. Give an example of the reaction.

1 Expert Answer

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Stasik P. answered • 10/11/20

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5th Year PhD student in Organic Chemistry at UCLA

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Hi Heyam,

Treating ether with strong acid and nucleophile will result in protonation of the ether to give an oxonium followed by an SN2 reaction to give an alcohol as well as a substitution product.


An example would be


EtOEt + HI. -------> EtI + EtOH


Let me know if anything doesn't make sense!

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