How to determine sensitivity in a dose-response curve?

Question

In a dose-response curve the % inhibition can be plotted against concentration antagonist. In our case, the effect of the antagonist is tested in different genetic variants of a microbe.When trying to determine the potency of a drug on the different variants, I compared the IC50 values. The lower the concentration required for 50% inhibition, the more potent the drug.When comparing drug efficacy, I compare the concentrations required to reach E_max or the maximum inhibition that each drug can exert - which turns out to be 100% inhibition.To compare sensitivity, how does one proceed?

Answer 1

One would think that sensitivity is an arbitrary measure and if you compare dose-response curves, ones that are left of others would show greater sensitivity, i.e. they would be affected at lower doses. Another way to look at this would be to set an arbitrary lower limit of inhibition, say 10%. Anything not inhibited 10% by a certain dose would be considered insensitive.