Do you mean "find the enthalpy"? To find entropy (S), we need to know more, such as either ∆G or Keq, or something else.
To find enthalpy: q = mC∆T = (50 g)(4.184 J/g/deg)(100 deg) = 20.920 J or 20.9 kJ = ∆H
If you had constant pressure and constant temp (which you do not), one can estimate CHANGE IN ENTROPY as
∆S = -∆H/T = - 20,920 J/373K = 56.1 kJ/K