if two animals with different chromosomes breed, does the sperm still fertilize the egg? when does the egg reject the sperm? what stage? (1 week, 2 week)

Question

when there are two animals with different chromosomes (not even close) does the sperm still try to fertilize the egg? at what stage does the egg finally reject it? I am sure it couldn't be immediately. so there would have to be a time frame. 

Answer 1

A quick "google" provided

http://www.madsci.org/posts/archives/2012-06/1338620243.Ge.r.html