I like to use an acronym I learned form a High School Student, CONI POI
Combination
Order
Not
Important
Permutation
Order
Important
Now they tell us right away that order doesn't mater, so we automatically know we are going to use a Combination.
so it is 49C6, or 49 Choose 6. Most calculators have Combinations and Permutations readily available but I'll say yours does not so lets get the formula for Combinations:
nCr = n! ÷ r!(n-r)!
the ! means factorial. In our case, n=49 and r=6, so lets put those in the formula
49C6 = 49! ÷ 6!(49-6)! = 49! ÷ (6!*43!)
That value you can put into your calculator and get the answer for the first 6 numbers chosen.
13,983,816 possible tickets.
Once we have that, then we must consider the powerball from another set of 10 numbers. Now think about it this way, if you have 2 pairs of pants and 10 shirts, you can wear each shirt with 10 different pants and have a different outfit. Since you have 2 shirts, you have 10 outfits for each shirt, so in total 20 outfits, or 2 times 10.
So once we figure out the number of possible tickets for the first 6 numbers, we simply multiply that by the powerball options, 10, and we will arrive at our answer.
139,838,160