Reaction of amines

Question

Describe the  reaction of phenyl amine with ethanoyl chloride.

Answer 1

Hi Sam

 

Treating phenyl amine with ethanoyl chloride (an acyl chloride) proceeds via a nucleophilic acyl substitution reaction and the resulting product as an amide, a carboxylic acid derivative. Acylation of the amino group is a useful synthetic strategy for electrophilic substitution reactions as the resulting amide group is a moderate activator (the amino group is a strong activator).

 

Hope this answers your question.