Navin P. answered • 02/09/24
Pharmacology Tutor with Biochemistry Experience
The combination of Mifepristone and Misoprostol is a commonly used method for medical abortion up to the first 10 weeks of pregnancy. Here's how each medication works in the process:
Mifepristone: The first medication taken is Mifepristone. Its primary function is to block the action of progesterone, a hormone essential for the continuation of pregnancy. Progesterone supports the pregnancy by maintaining the uterine lining (endometrium), where the fertilized egg implants and grows. By blocking progesterone, Mifepristone causes the lining of the uterus to thin and prevents the embryo from staying implanted and growing.
Misoprostol: Following the administration of Mifepristone, Misoprostol is taken 24 to 48 hours later. Misoprostol causes the uterus to contract and expel the embryo through the vagina. These contractions are similar to menstrual cramps but can be significantly stronger. Misoprostol also helps in dilating the cervix (the opening to the uterus), which aids in the expulsion process. The contractions and dilation help to expel the pregnancy tissue out of the uterus.
The combination of these two drugs makes the process of medical abortion similar to a miscarriage. The process can take a few hours to a couple of days to complete. It is important for individuals undergoing this form of abortion to have access to medical support and follow-up care to ensure the process is complete and to manage any potential side effects or complications
