This is a “u substitution” question, which you can recognize by seeing that the numerator of the integrand is basically the derivative of the denominator (times a constant).
Let u = 1 + 4tan(3x).
Then differentiate: du = 12sec2(3x)dx
Then substitute: 1/12 ∫(1/u)du
And integrate: = 1/12⋅ln|u| + C
Finally, re-substitute: 1/12⋅ln|1+4tan(3x)| + C