​​Order:​ Itraconazole​​ (Sporanox) 4​​ mg/kg/d divided in equal dosages q.8h. ​The​ multi-dose vial label​ reads​ "10​ mg/mL."How many milliliters will you administer to a client who weighs​ 85​ kg?

Answer 1

This is a 2-step ratio problem. We start by calculating the amount of medication she needs per day.

The patient is 85 kg, and for every 1 kg she'll need 4 mg of itraconazole. So the ratio is 4 mg itraconazole / 1 kg

And for every 1 ml of the available solution, there's 10 mg of itraconazole. So the ratio is 1 ml / 10 mg itraconazole

1. 85 kg ( 4 mg itraconazole / 1 kg) ( 1 ml / 10 mg itraconazole) = 34 ml per day
2. To get the amount per dose we divide by 3
3. 34 ml / 3 = 11.3 ml per dose

Notice how the units cancel and you are left with just ml, which is the correct unit.

Answer 2

4 mg = x x = 340 mg ( the amount in mg needed for 85 kg patient)

1 kg 85

10 mg = 340 mg x = 34 ml ( amount in ml patient needs every 8 hours or 3 times a day)

1 ml x