How would the failure of elongation during transcription differ from a failure of elongation during translation

Question

Gene is undergoing transcription and translation to produce protein. How would the failure of elongation during transcription differ from a failure of elongation during translation. what is true for production of gene?

-no protein would be make? transciption failed or translation failed

transcription would still occur if translation failed or the oppsition translation would still occur it transciption failed. -RNA polymerase would function normally

-tRNA would be be able to bind their amino acids.

Answer 1

Lets review what transcription is and what translation is:

Transcription is the generation of RNA from DNA. That RNA holds data for what kind of protein will be made. Initial RNA is hnRNA (heterogeneous nuclear RNA) which then becomes mRNA. There are various other steps as well including adding poly A tails, nuclear capping, etc. There is no "Elongation" occuring in transcription. Defects and mutations in transcription, day for instance from an amanita phalloides toxin which targets RNA polymerase 2, would halt all transcription.

Translation takes that RNA and builds protein through processes of initiation, ELONGATION, and termination. If there is a defect in Elongation, depending on if it's in the beginning or towards the end, the protein may either not be formed, may be small, or may be large and bulky. Transcription still occurs, but there is a defect in Elongation causing stunted protein growth/formation.

Hope that helps