Is there any specific event that lead to the Ottomans succeeding the Byzantines?

Question

I'm covering this topic for my NHD topic, hopefully you can tell me if there was any one event that could've led to the Ottomans to domination over Anatolia and the Balkans.

Answer 1

In a word, no. A series of back and forth conflicts resulted in the conquest of Constantinople on 29 May 1453.