I'm not sure what f(-) is. I think you left out the actual number, but here's how it works.
If: f(n) = 5n + 1
Then: f(-1) = 5·(-1) + 1 = -5 + 1 = -4
Just replace the n with -1 and compute the value. If it's f(2), replace the n with 2. Remember that 5n is 5 times n, so if you replace n with an actual number, it's 5 times that number.