Let A be the event: the card chosen is red
Let B be the event: the card chosen is a 5
A and B are independent if P(A and B) = P(A)P(B)
P(A and B) = P(a red 5 was chosen) = 2/52 = 1/26
P(A)P(B) = (1/2)(4/52) = 1/26
Since P(A and B) = P(A)P(B), the events (A and B) are independent.