Alex S. answered 05/17/15
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Assuming you can use the letters and numbers again once they have already been used (i.e., if the first letter of the license plate is a B, you are able to use B again for any/some/all of the other three letters), then you just have to think about how many possibilities there are for each space of the license plate. For the first space, the only possibilities are all of the letters of the alphabet. That would be 26. The same holds true for the next 3 spaces (26 possibilities for each of them). Then for the 5th space, the only possibilities are digits. There are 10 digits (0-9). Same thing for the last space on the license plate. The total amount of license plates are figured out by multiplying each space together. So the answer is computed as: 26x26x26x26x10x10. Therefore, there are 45,697,600 possible license plates given the constraints in the question.
If you have any questions, feel free to reach out to me. And if you can't re-use the letters and numbers you previously used, then the answer is similar, but you need to think about it a little differently. I am happy to explain that to you. I hope this helps.