Mark M. answered 04/09/20
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Retired math prof. Very extensive Precalculus tutoring experience.
If c is a root, then x - c is a factor
f(x) = a(x+4)(x-1)
Since f(0) = 16, we have -4a = 16. so, a = -4.
Therefore, f(x) = -4(x+4)(x-1) = -4(x2 + 3x - 4) = -4x2 - 12x +16