I teach pre-Nursing Anatomy and Physiology, so I try to give my students a general overview of the body system as it relates to other physiology, and then the medical concerns they might encounter as they progress in their career path.
Endocrine and Nervous System are the command control systems to coordinate our 37.5 trillion cells. Nervous system offers rapid fire but short lived signals, using neurotransmitters emitted very close to their target, that will be cleared quickly. Endocrine Hormones are also chemical signals, but they are secreted into the bloodstream, and the signal heard in the distant cells are only effective if the cells have a receptor specific to that chemical signal. Hormone signals must be cleared from the blood stream, so the signal is slower to be received than neurotransmitters in the nervous system, and can also be much longer lived.
Hormonal controls are therefore complex. Some hormones oppose each other, for example, insulin lowers blood glucose by docking in our cell's insulin receptors to get the cell to invite the glucose in from the bloodstream. Glucagon is insulin's antagonist, and raises blood glucose by ordering liver to release glucose into blood stream, especially for the brain to be able to be supplied with constant glucose and energy (brain has no energy reserves so it desperately depends on the liver to keep blood glucose high enough to keep it going).
Both hormones operate on a negative feedback loop. This means for example, after a breakfast of Cheerios, when blood glucose rises from absorption of all those carbs, insulin is metered out by pancreas to lower blood glucose and keep it within homeostasis. When blood glucose returns to normal, pancreas stops secreting insulin, or else blood glucose would go too low, and brain would be trouble.
So blood glucose stability/homeostasis, is governed by at least these 2 antagonist hormones, both on a negative feedback loop. Does that give us information about how important blood glucose homeostasis is to the homeostasis of the rest of the body?
Some hormones are antagonists, some permit others to work, some work as synergists with others, meaning together they get the job done perfectly. Hormonal control is therefore really complicated!
And the major thing to remember, Hypothalamus in the brain is in control of the Pituitary Gland in brain, which is considered the master controller of other glands around the body. So the brain is the Boss!
This is just a brief overview of basic principles, then there are all those acronyms! (GH, GNRH, ADH, so many more!!)
Does this help you?