The first thing to do here is to factor everything and recognize that we are dividing by the last term. Recall that when you divide by a fraction, it is the same as multiplying by the reciprocal of that fraction.
So,
10x2y • (x+y)2 • 5y2
x2+xy 2x x2-y2
Notice I've flipped the last term and am multiplying rather than dividing.
Now let's factor each term.
10x2y • (x+y)2 • 5y2
x(x+y) 2x (x+y)(x-y)
x(x+y) 2x (x+y)(x-y)
Removing the bolded terms, we have
10x2y 5y2
x 2x (x-y)
x 2x (x-y)
Continuing in this fashion
10x2y 5y2
x 2x (x-y)
x 2x (x-y)
Removing the marked x's
10y 5y2
2 (x-y)
Since 10/2 = 5, we are left with
5y 5y2 = 25y3
(x-y) (x-y)
(x-y) (x-y)
Hope this has been of help.

Marlene S.
12/30/15