x

^{-3}y^{-5}.-2yx^{2}/(-2x^{-3}y^{4})^{5}=x^{-3}y^{-5}.-2yx^{2}/(-2x^{-3}y^{4})^{5}=

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X^{-3 }y ^{-5} * (- 2) Y X^{2 } / ( -2 X^{-3} Y^{4} )^{5 =}

- 2Y X^{2} / (-2) ^{5 }X^{-15 } Y^{20 = }X ^{17} / 16 Y^{20}

Just use the laws of Multiplication of exponents with the same base, and also negative exponents.

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