Difficulty in finding protein inhibition drugs?

I was reading an article on a recent identification of a PARP-14 protein in cancer cells that is responsible for production of additional glucose which keeps cancer cells from dying, and that a... more

04/23/19

How is the selectivity of a drug ensured?

How is a drug created that would target a particular site? I always wonder when I take a pill for headache, how the pill knows that its my head and not my knee. Or is it that it interacts with all... more

If a human takes antibiotics are all bacteria in the body killed?

From my basic understanding, antibiotics kill living things, bacteria for example. Do the antibiotics consumed by a human-being distinguish between what they kill? Or do they just kill every... more

Is half-a-tablet of X a substitute for a tablet of X/2?

This may be anecdotal. At the pharmacy earlier, the prescription called for a drug with X mg of the target chemical. The pharmacy however only had stock of a higher potency of the same brand. E.g.... more

How many sildenafil tablets each containing 500 mcg can be prepared from 1g of sildenafil?

2,000 tabletsConversion: 1 g = 1000000 mcg 1 g = 1000000 mcg 1000000 mcg / 500 mcg = 2000 tablets

How does aspirin "thin" blood?

As we all know, aspirin doesn't actually "thin" the blood, as it has been explained to me, it makes it "slippery". Slippery blood doesn't stick to itself hence this helps prevent internal blood... more

Popular science books introducing therapeutic use of psychedelic drugs?

I'm not a psychologist nor a psychiatrist, but I have the impression that research of therapeutic use of psychedelic drugs (MDMA, LSD, DMT, etc) is undergoing a revival and is very slowly being... more

How does drug-induced photosensitivity work?

Some drugs (tetracyclines, for instance) can cause photosensitivity reactions—that is, some patients become extremely sensitive to the sun, developing rashes or inflammation after spending time in... more

Why does Penicillin only affect bacterial cell walls?

I was quite fascinated by the feature [Should Science Pull the Trigger on Antiviral Drugs—That Can Blast the Common Cold?](http://www.wired.com/wiredscience/2012/03/ff_antivirals/) in this month's... more

03/27/19

Why is Paracetamol so great?

Every time I get ill (cold, flu etc) I take a couple of these wonderful tablets for up to 4 times a day and I, eventually, get better. What exactly is paracetamol? Why is it so effective and is... more

Why does the weight matter when consuming a certain amount of a specific drug?

My question is actually referred to hallucinogenic substances, in particular to mushrooms.I can understand why alcohol or other substances that relate to body mass (fat in some cases) affect people... more

How exactly does marijuana damage brain cells?

I've heard that THC can cause permanent damage to brain cells. I've also heard this reffered to anti drug propaganda. Another theory i've read is that temporary effects reduce intelligence but long... more

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